Recombinant Human CLNK Protein, GST-tagged

• Cat.No.: CLNK-1508H
• Product Overview: Human CLNK full-length ORF (BAG52635.1, 1 a.a. - 428 a.a.) recombinant protein with GST tag at N-terminal.

Specification

• Description: MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76 kDa
• AA Sequence: MNRQGNRKTTKEGSNDLKFQNFSLP KNRSWPRINSATGQYQRMNKPLLDW ERNFAAVLDGAKGHSDDDYDDPELR MEETWQSIKILPARPIKESEYADTH YFKVAMDTPLPLDTRTSISIGQPTW NTQTRLERVDKPISKDVRSQNIKGD ASVRKNKIPLPPPRPLITLPKKYQP LPPEPESSRPPLSQRHTFPEVQRMP SQISLRDLSEVLEAEKVPHNQRKPE STHLLENQNTQEIPLAISSSSFTTS NHSVQNRDHRGGMQPCSPQRCQPPA SCSPHENILPYKYTSWRPPFPKRSD RKDVQHNEWYIGEYSRQAVEEAFMK ENKDGSFLVRDCSTKSKEEPYVLAV FYENKVYNVKIRFLERNQQFALGTG LRGDEKFDSVEDIIEHYKNFPIILI DGKDKTGVHRKQCHLTQPLPLTRHL LPL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLNK cytokine-dependent hematopoietic cell linker [ Homo sapiens ]
• Official Symbol: CLNK
• Synonyms: CLNK; cytokine-dependent hematopoietic cell linker; mast cell immunoreceptor signal transducer; MIST; MGC35197
• Gene ID: 116449
• mRNA Refseq: NM_052964
• Protein Refseq: NP_443196
• MIM: 611434
• UniProt ID: Q7Z7G1