Recombinant Human CLPS Protein, MYC/DDK-tagged

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Recombinant Human CLPS Protein, MYC/DDK-tagged

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Cat.No. : CLPS-3260H
Product Overview : Recombinant Human CLPS protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 10.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CLPS colipase, pancreatic [Homo sapiens]
Official Symbol : CLPS
Synonyms : OTTHUMP00000016271; colipase; pancreatic colipase preproprotein; colipase, pancreatic
Gene ID : 1208
mRNA Refseq : NM_001832
Protein Refseq : NP_001823
MIM : 120105
UniProt ID : P04118

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