Recombinant Human CLTA, GST-tagged

• Cat.No.: CLTA-11353H
• Product Overview: Recombinant Human CLTA protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-218a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CLTA clathrin, light chain A [ Homo sapiens ]
• Official Symbol: CLTA
• Synonyms: CLTA; clathrin, light chain A; clathrin, light polypeptide (Lca); clathrin light chain A; Lca; LCA
• Gene ID: 1211
• mRNA Refseq: NM_001076677
• Protein Refseq: NP_001070145
• MIM: 118960
• UniProt ID: P09496
• Chromosome Location: 9p13.3
• Pathway: Arf1 pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Developmental Biology, organism-specific biosystem
• Function: molecular_function; peptide binding; structural molecule activity