Recombinant Human CNOT2 Protein, GST-tagged

• Cat.No.: CNOT2-1578H
• Product Overview: Human CNOT2 full-length ORF ( AAH02597, 1 a.a. - 540 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.14 kDa
• AA Sequence: MVRTDGHTLSEKRNYQVTNSMFGAS RKKFVEGVDSDYHDENMYYSQSSMF PHRSEKDMLASPSTSGQLSQFGASL YGQQSALGLPMRGMSNNTPQLNRSL SQGTQLPSHVTPTTGVPTMSLHTPP SPSRGILPMNPRNMMNHSQVGQGIG IPSRTNSMSSSGLGSPNRSSPSIIC MPKQQPSRQPFTVNSMSGFGMNRNQ AFGMNNSLSSNIFNGTDGSENVTGL DLSDFPALADRNRREGSGNPTPLIN PLAGRAPYVGMVTKPANEQSQDFSI HNEDFPALPGSSYKDPTSSNDDSKS NLNTSGKTTSSTDGPKFPGDKSSTT QNNNQQKKGIQVLPDGRVTNIPQGM VTDQFGMIGLLTFIRAAETDPGMVH LALGSDLTTLGLNLNSPENLYPKFA SPWASSPCRPQDIDFHVPSEYLTNI HIRDKLAAIKLGRYGEDLLFYLYYM NGGDVLQLLAAVELFNRDWRYHKEE RVWITRAPGMEPTMKTNTYERGTYY FFDCLNWRKVAKEFHLEYDKLEERP HLPSTFNYNPAQQAF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CNOT2 CCR4-NOT transcription complex, subunit 2 [ Homo sapiens ]
• Official Symbol: CNOT2
• Synonyms: CNOT2; CCR4-NOT transcription complex, subunit 2; NOT2; CCR4-NOT transcription complex subunit 2; CDC36; NOT2H; CCR4-associated factor 2; negative regulator of transcription 2; HSPC131; FLJ26456
• Gene ID: 4848
• mRNA Refseq: NM_001199302
• Protein Refseq: NP_001186231
• MIM: 604909
• UniProt ID: Q9NZN8