Recombinant Human COCH Protein, GST-tagged
Cat.No. : | COCH-1619H |
Product Overview : | Human COCH full-length ORF ( AAH07230.1, 1 a.a. - 494 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 79.6 kDa |
AA Sequence : | MSAAWIPALGLGVCLLLLPGPAGSE GAAPIAITCFTRGLDIRKEKADVLC PGGCPLEEFSVYGNIVYASVSSICG AAVHRGVISNSGGPVRVYSLPGREN YSSVDANGIQSQMLSRWSASFTVTK GKSSTQEATGQAVSTAHPPTGKRLK KTPEKKTGNKDCKADIAFLIDGSFN IGQRRFNLQKNFVGKVALMLGIGTE GPHVGLVQASEHPKIEFYLKNFTSA KDVLFAIKEVGFRGGNSNTGKALKH TAQKFFTVDAGVRKGIPKVVVVFID GWPSDDIEEAGIVAREFGVNVFIVS VAKPIPEELGMVQDVTFVDKAVCRN NGFFSYHMPNWFGTTKYVKPLVQKL CTHEQMMCSKTCYNSVNIAFLIDGS SSVGDSNFRLMLEFVSNIAKTFEIS DIGAKIAAVQFTYDQRTEFSFTDYS TKENVLAVIRNIRYMSGGTATGDAI SFTVRNVFGPIRESPNKNFLVIVTD GQSYDDVQGPAAAAHDAAK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | COCH coagulation factor C homolog, cochlin (Limulus polyphemus) [ Homo sapiens ] |
Official Symbol : | COCH |
Synonyms : | COCH; coagulation factor C homolog, cochlin (Limulus polyphemus); coagulation factor C (Limulus polyphemus homolog); cochlin , DFNA9, DFNA31; cochlin; COCH 5B2; DFNA9; COCH5B2; COCH-5B2; |
Gene ID : | 1690 |
mRNA Refseq : | NM_001135058 |
Protein Refseq : | NP_001128530 |
MIM : | 603196 |
UniProt ID : | O43405 |
Products Types
◆ Recombinant Protein | ||
COCH-781R | Recombinant Rhesus Macaque COCH Protein, His (Fc)-Avi-tagged | +Inquiry |
COCH-1840M | Recombinant Mouse COCH Protein, His (Fc)-Avi-tagged | +Inquiry |
COCH-6497C | Recombinant Chicken COCH | +Inquiry |
COCH-1119Z | Recombinant Zebrafish COCH | +Inquiry |
COCH-15H | Recombinant Human COCH protein, FLAG-tagged | +Inquiry |
◆ Lysates | ||
COCH-2373HCL | Recombinant Human COCH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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