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- Human(5)
- Mouse(2)
- Rhesus Macaque(1)
- Zebrafish(1)
Recombinant Human COCH Protein, GST-tagged
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| Cat.No. : | COCH-1619H |
| Product Overview : | Human COCH full-length ORF ( AAH07230.1, 1 a.a. - 494 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : | The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008] |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | GST |
| Molecular Mass : | 79.6 kDa |
| AA Sequence : | MSAAWIPALG LGVCLLLLPG PAGSEGAAPI AITCFTRGLD IRKEKADVLC PGGCPLEEFS VYGNIVYASV SSICGAAVHR GVISNSGGPV RVYSLPGREN YSSVDANGIQ SQMLSRWSAS FTVTKGKSST QEATGQAVST AHPPTGKRLK KTPEKKTGNK DCKADIAFLI DGSFNIGQRR FNLQKNFVGK VALMLGIGTE GPHVGLVQAS EHPKIEFYLK NFTSAKDVLF AIKEVGFRGG NSNTGKALKH TAQKFFTVDA GVRKGIPKVV VVFIDGWPSD DIEEAGIVAR EFGVNVFIVS VAKPIPEELG MVQDVTFVDK AVCRNNGFFS YHMPNWFGTT KYVKPLVQKL CTHEQMMCSK TCYNSVNIAF LIDGSSSVGD SNFRLMLEFV SNIAKTFEIS DIGAKIAAVQ FTYDQRTEFS FTDYSTKENV LAVIRNIRYM SGGTATGDAI SFTVRNVFGP IRESPNKNFL VIVTDGQSYD DVQGPAAAAH DAAK |
| Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing: : |
12.5% SDS-PAGE Stained with Coomassie Blue. |
| Gene Name : | COCH coagulation factor C homolog, cochlin (Limulus polyphemus) [ Homo sapiens ] |
| Official Symbol : | COCH |
| Synonyms : | COCH; coagulation factor C homolog, cochlin (Limulus polyphemus); coagulation factor C (Limulus polyphemus homolog); cochlin , DFNA9, DFNA31; cochlin; COCH 5B2; DFNA9; COCH5B2; COCH-5B2; |
| Gene ID : | 1690 |
| mRNA Refseq : | NM_001135058 |
| Protein Refseq : | NP_001128530 |
| MIM : | 603196 |
| UniProt ID : | O43405 |
◆ Recombinant Protein
| COCH-3704M | Recombinant Mouse COCH Protein | +Inquiry |
| COCH-3207H | Recombinant Human COCH, His tagged | +Inquiry |
| COCH-15H | Recombinant Human COCH protein, FLAG-tagged | +Inquiry |
| COCH-956R | Recombinant Rhesus monkey COCH Protein, His-tagged | +Inquiry |
| COCH-3899H | Recombinant Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) | +Inquiry |
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◆ Lysates
| COCH-2373HCL | Recombinant Human COCH cell lysate | +Inquiry |
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