Recombinant Human COL9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human COL9A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : COL9A1-5853H
Product Overview : COL9A1 MS Standard C13 and N15-labeled recombinant protein (NP_511040) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 64.4 kDa
AA Sequence : MAWTARDRGA LGLLLLGLCL CAAQRGPPGE QGPPGPPGPP GVPGIDGIDG DRGPKGPPGP PGPAGEPGKP GAPGKPGTPG ADGLTGPDGS PGSIGSKGQK GEPGVPGSRG FPGRGIPGPP GPPGTAGLPG ELGRVGPVGD PGRRGPPGPP GPPGPRGTIG FHDGDPLCPN ACPPGRSGYP GLPGMRGHKG AKGEIGEPGR QGHKGEEGDQ GELGEVGAQG PPGAQGLRGI TGIVGDKGEK GARGLDGEPG PQGLPGAPGD QGQRGPPGEA GPKGDRGAEG ARGIPGLPGP KGDTGLPGVD GRDGIPGMPG TKGEPGKPGP PGDAGLQGLP GVPGIPGAKG VAGEKGSTGA PGKPGQMGNS GKPGQQGPPG EVGPRGPQGL PGSRGELGPV GSPGLPGKLG SLGSPGLPGL PGPPGLPGMK GDRGVVGEPG PKGEQGASGE EGEAGERGEL GDIGLPGPKG SAGNPGEPGL RGPEGSRGLP GVEGPRGPPG PRGVQGEQGA TGLPGVQGPP GRAPTDQHIK QVCMRVIQEH FAEMAASLKR PDSGATGLPG RPGPPGPPGP PGENGFPGQM GIRGLPGIKG PPGALGLRGP KGDLGEKGER GPPGRGPNGL PGAIGLPGDP GPASYGRNGR DGERGPPGVA GIPGVPGPPG PPGLPGFCEP ASCTMQAGQR AFNKGPDPTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : COL9A1 collagen type IX alpha 1 chain [ Homo sapiens (human) ]
Official Symbol : COL9A1
Synonyms : COL9A1; collagen, type IX, alpha 1; collagen alpha-1(IX) chain; alpha-1(IX) collagen chain; collagen IX, alpha-1 polypeptide; cartilage-specific short collagen; MED; EDM6; STL4; DJ149L1.1.2; FLJ40263;
Gene ID : 1297
mRNA Refseq : NM_078485
Protein Refseq : NP_511040
MIM : 120210
UniProt ID : P20849

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