Recombinant Human COQ6 Protein, GST-tagged
Cat.No. : | COQ6-1719H |
Product Overview : | Human COQ6 full-length ORF ( AAH14181, 1 a.a. - 468 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 77.22 kDa |
AA Sequence : | MAARLVSRCGAVRAAPHSGPLVSWR RWSGASTDTVYDVVVSGGGLVGAAM ACALGYDIHFHDKKILLLEAGPKKV LEKLSETYSNRVSSISPGSATLLSS FGAWDHICNMRYRAFRRMQVWDACS EALIMFDKDNLDDMGYIVENDVIMH ALTKQLEAVSDRVTVLYRSKAIRYT WPCPFPMADSSPWVHITLGDGSTFQ TKLLIGADGHNSGVRQAVGIQNVSW NYDQSAVVATLHLSEATENNVAWQR FLPSGPIALLPLSDTLSSLVWSTSH EHAAELVSMDEEKFVDAVNSAFWSD ADHTDFIDTAGAMLQYAVSLLKPTK VSARQLPPSVARVDAKSRVLFPLGL GHAAEYVRPRVALIGDAAHRVHPLA GQGVNMGFGDISSLAHHLSTAAFNG KDLGSVSHLTGYETERQRHNTALLA ATDLLKRLYSTSASPLVLLRTWGLQ ATNAVSPLKEQIMAFASK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | COQ6 coenzyme Q6, monooxygenase [ Homo sapiens (human) ] |
Official Symbol : | COQ6 |
Synonyms : | COQ6; coenzyme Q6, monooxygenase; Coenzyme Q6, Monooxygenase; Coenzyme Q10 Monooxygenase 6; Ubiquinone Biosynthesis Monooxygenase COQ6, Mitochondrial; Coenzyme Q6 Homolog, Monooxygenase (S. Cerevisiae); Coenzyme Q6 Homolog, Monooxygenase (Yeast); Coenzyme Q6 Homolog, Monooxygenase; Coenzyme Q6 Homolog (Yeast); Coenzyme Q6 Monooxygenase; EC 1.14.13.-; EC 1.14.13; COQ10D6; CGI-10; CGI10; ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; coenzyme Q10 monooxygenase 6; coenzyme Q6 homolog, monooxygenase |
Gene ID : | 51004 |
mRNA Refseq : | NM_182476 |
Protein Refseq : | NP_872282 |
MIM : | 614647 |
UniProt ID : | Q9Y2Z9 |
Products Types
◆ Recombinant Protein | ||
COQ6-1198R | Recombinant Rat COQ6 Protein, His (Fc)-Avi-tagged | +Inquiry |
COQ6-1899M | Recombinant Mouse COQ6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Coq6-1587R | Recombinant Rat Coq6 protein, His & T7-tagged | +Inquiry |
COQ6-4367Z | Recombinant Zebrafish COQ6 | +Inquiry |
COQ6-493H | Recombinant Human COQ6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
COQ6-192HCL | Recombinant Human COQ6 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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