| Description : |
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
116.3 kDa |
| AA Sequence : |
MKQSPALAPEERCRRAGSPKPVLRA DDNNMGNGCSQKLATANLLRFLLLV LIPCICALVLLLVILLSYVGTLQKV YFKSNGSEPLVTDGEIQGSDVILTN TIYNQSTVVSTAHPDQHVPAWTTDA SLPGDQSHRNTSACMNITHSQCQML PYHATLTPLLSVVRNMEMEKFLKFF TYLHRLSCYQHIMLFGCTLAFPECI IDGDDSHGLLPCRSFCEAAKEGCES VLGMVNYSWPDFLRCSQFRNQTESS NVSRICFSPQQENGKQLLCGRGENF LCASGICIPGKLQCNGYNDCDDWSD EAHCNCSENLFHCHTGKCLNYSLVC DGYDDCGDLSDEQNCDCNPTTEHRC GDGRCIAMEWVCDGDHDCVDKSDEV NCSCHSQGLVECRNGQCIPSTFQCD GDEDCKDGSDEENCSVIQTSCQEGD QRCLYNPCLDSCGGSSLCDPNNSLN NCSQCEPITLELCMNLPYNSTSYPN YFGHRTQKEASISWESSLFPALVQT NCYKYLMFFSCTILVPKCDVNTGEH IPPCRALCEHSKERCESVLGIVGLQ WPEDTDCSQFPEENSDNQTCLMPDE YVEECSPSHFKCRSGQCVLASRRCD GQADCDDDSDEENCGCKERDLWECP SNKQCLKHTVICDGFPDCPDYMDEK NCSFCQDDELECANHACVSRDLWCD GEADCSDSSDEWDCVTLSINVNSSS FLMVHRAATEHHVCADGWQEILSQL ACKQMGLGEPSVTKLIQEQEKEPRW LTLHSNWESLNGTTLHELLVNGQSC ESRSKISLLCTKQDCGRRPAARMNK RILGGRTSRPGRWPWQCSLQSEPSG HICGCVLIAKKWVLTVAHCFEGREN AAVWKVVLGINNLDHPSVFMQTRFV KTIILHPRYSRAVVDYDISIVELSE DISETGYVRPVCLPNPEQWLEPDTY CYITGWGHMGNKMPFKLQEGEVRII SLEHCQSYFDMKTITTRMICAGYES GTVDSCMGDSGGPLVCEKPGGRWTL FGLTSWGSVCFSKVLGPGVYSNVSY FVEWIKRQIYIQTFLLNTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
