Recombinant Human CPT1A Protein, Myc/DDK-tagged

• Cat.No.: CPT1A-02H
• Product Overview: Recombinant protein of human carnitine palmitoyltransferase 1A (liver) (CPT1A), nuclear gene encoding mitochondrial protein, transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 88.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: CPT1A carnitine palmitoyltransferase 1A [ Homo sapiens (human) ]
• Official Symbol: CPT1A
• Synonyms: CPT1A; carnitine palmitoyltransferase 1A; CPT1; CPT1-L; L-CPT1; carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPTI-L; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; EC 2.3.1.21
• Gene ID: 1374
• mRNA Refseq: NM_001876
• Protein Refseq: NP_001867
• MIM: 600528
• UniProt ID: P50416