Recombinant Human CREM Protein, His&GST-tagged

• Cat.No.: CREM-840H
• Product Overview: Recombinant Human CREM Protein (Met1-Glu182) with His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 49.7 kDa; Accurate Molecular Mass: 50 kDa
• Protein length: Met1-Glu182
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CREM cAMP responsive element modulator [ Homo sapiens (human) ]
• Official Symbol: CREM
• Synonyms: CREM; cAMP responsive element modulator; cAMP-responsive element modulator; hCREM 2; CREM 2beta-a protein; CREM 2alpha-b protein; cAMP response element modulator; inducible cAMP early repressor ICER; ICER; CREM-2; hCREM-2; MGC17881; MGC41893; MGC111110
• Gene ID: 1390
• mRNA Refseq: NM_001881
• Protein Refseq: NP_001872
• MIM: 123812
• UniProt ID: Q03060