Recombinant Human CRKL Protein, His-tagged CRKL-561H

Cat.No. :	CRKL-561H
Product Overview :	Recombinant Human CRKL(Met1~Glu303) fused with His tag at N-terminal was expressed in E. coli.
Description :	This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Source :	E. coli
Species :	Human
Tag :	His
Form :	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass :	37.5kDa
Protein length :	Met1~Glu303
Endotoxin :	<1.0EU per 1µg (determined by the LAL method)
Purity :	> 98%
Applications :	Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution :	Reconstitute in PBS or others.
Figure :

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Gene Name :	CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like [ Homo sapiens ]
Official Symbol :	CRKL
Synonyms :	CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v crk avian sarcoma virus CT10 oncogene homolog like; crk-like protein;
Gene ID :	1399
mRNA Refseq :	NM_005207
Protein Refseq :	NP_005198
MIM :	602007
UniProt ID :	P46109