- Human(6)
- Rhesus Macaque(1)
- Zebrafish(1)
Recombinant Human CSE1L Protein, GST-tagged
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Cat.No. : | CSE1L-1959H |
Product Overview : | Human CSE1L full-length ORF ( ENSP00000343253, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 49.1 kDa |
AA Sequence : | MELSDANLQT LTEYLKKTLD PDPAIRRPAE KFLESVEGNQ NYPLLLLTLL EKSQDNVIKV CASVTFKNYI KRNWRIVEDE PNKICEADRV AIKANIVHLM LSSPEQIQKQ LSDAISIIGR EDFPQKWPDL LTEMVNRFQS GDFHVINGVL RTAHSLFKRY RHEFKSNELW TEIKLVLDAF ALPLTNLFKV WNASW |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing: : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | CSE1L CSE1 chromosome segregation 1-like (yeast) [ Homo sapiens ] |
Official Symbol : | CSE1L |
Synonyms : | CSE1L; CSE1 chromosome segregation 1-like (yeast); chromosome segregation 1 (yeast homolog) like; exportin-2; CAS; CSE1; XPO2; exp2; importin-alpha re-exporter; chromosome segregation 1-like protein; cellular apoptosis susceptibility protein; MGC117283; MGC130036; MGC130037; |
Gene ID : | 1434 |
mRNA Refseq : | NM_001256135 |
Protein Refseq : | NP_001243064 |
MIM : | 601342 |
UniProt ID : | P55060 |
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