Recombinant Human CTH Protein, GST-tagged

• Cat.No.: CTH-2070H
• Product Overview: Human CTH full-length ORF ( AAH15807, 1 a.a. - 405 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 70.07 kDa
• AA Sequence: MQEKDASSQGFLPHFQHFATQAIHV GQDPEQWTSRAVVPPISLSTTFKQG APGQHSGFEYSRSGNPTRNCLEKAV AALDGAKYCLAFASGLAATVTITHL LKAGDQIICMDDVYGGTNRYFRQVA SEFGLKISFVDCSKIKLLEAAITPE TKLVWIETPTNPTQKVIDIEGCAHI VHKHGDIILVVDNTFMSPYFQRPLA LGADISMYSATKYMNGRSDVVMGLV SVNCESLHNRLRFLQNSLGAVPSPI DCYLCNRGLKTLHVRMEKHFKNGMA VAQFLESNPWVEKVIYPGLPSHPQH ELVKRQCTGCTGMVTFYIKGTLQHA EIFLKNLKLFTLAESLGGFESLAEL PAIMTHASVLKNDRDVLGISDTLIR LSVGLEDEEDLLEDLDQALKAAHPP SGSHS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CTH cystathionase (cystathionine gamma-lyase) [ Homo sapiens ]
• Official Symbol: CTH
• Synonyms: CTH; cystathionase (cystathionine gamma-lyase); cystathionine gamma-lyase; gamma-cystathionase; homoserine deaminase; cysteine desulfhydrase; homoserine dehydratase; cysteine-protein sulfhydrase; MGC9471
• Gene ID: 1491
• mRNA Refseq: NM_001190463
• Protein Refseq: NP_001177392
• MIM: 607657
• UniProt ID: P32929