Recombinant Human CTNS Protein, MYC/DDK-tagged

• Cat.No.: CTNS-2091H
• Product Overview: Purified recombinant protein of Homo sapiens cystinosis, nephropathic (CTNS), transcript variant 2 with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 41.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: CTNS cystinosin, lysosomal cystine transporter [ Homo sapiens (human) ]
• Official Symbol: CTNS
• Synonyms: CTNS; cystinosin, lysosomal cystine transporter; PQLC4; SLC66A4; CTNS-LSB; cystinosin; cystinosis nephropathic
• Gene ID: 1497
• mRNA Refseq: NM_004937
• Protein Refseq: NP_004928
• MIM: 606272
• UniProt ID: O60931