Recombinant Human CUEDC2 Protein, Myc/DDK-tagged, C13 and N15-labeled CUEDC2-5282H

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Recombinant Human CUEDC2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	CUEDC2-5282H
Product Overview :	CUEDC2 MS Standard C13 and N15-labeled recombinant protein (NP_076945) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	24.7 kDa
AA Sequence :	MELERIVSAA LLAFVQTHLP EADLSGLDEV IFSYVLGVLE DLGPSGPSEE NFDMEAFTEM MEAYVPGFAH IPRGTIGDMM QKLSGQLSDA RNKENLQPQS SGVQGQVPIS PEPLQRPEML KEETRSSAAA AADTQDEATG AEEELLPGVD VLLEVFPTCS VEQAQWVLAK ARGDLEEAVQ MLVEGKEEGP AAWEGPNQDL PRRLRGPQKD ELKSFILQKY MMVDSATRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	CUEDC2 CUE domain containing 2 [ Homo sapiens (human) ]
Official Symbol :	CUEDC2
Synonyms :	CUEDC2; CUE domain containing 2; C10orf66; bA18I14.5; CUE domain-containing protein 2
Gene ID :	79004
mRNA Refseq :	NM_024040
Protein Refseq :	NP_076945
MIM :	614142
UniProt ID :	Q9H467