Recombinant Human CXXC1, His-tagged

• Cat.No.: CXXC1-27242TH
• Product Overview: Recombinant fragment, corresponding to amino acids 250-632 of Human CGBP with an N terminal His tag. Predicted mwt: 46 kDa,

Specification

• Description: Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 92 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: KLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPD LYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKV KHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERAD AKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIY EILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTR LQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTD LQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPT RIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVP ADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLR RAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGL

Gene Information

• Gene Name: CXXC1 CXXC finger protein 1 [ Homo sapiens ]
• Official Symbol: CXXC1
• Synonyms: CXXC1; CXXC finger protein 1; CXXC finger 1 (PHD domain); cpG-binding protein; CFP1; CGBP; CpG binding protein; DNA binding protein with PHD finger and CXXC domain; hCGBP; HsT2645; PCCX1; PHF18; SPP1; ZCGPC1; zinc finger; CpG binding type containing 1
• Gene ID: 30827
• mRNA Refseq: NM_001101654
• Protein Refseq: NP_001095124
• MIM: 609150
• Uniprot ID: Q9P0U4
• Chromosome Location: 18q12
• Pathway: Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Unfolded Protein Response, organism-specific biosystem
• Function: DNA binding; contributes_to histone methyltransferase activity (H3-K4 specific); metal ion binding; protein binding; unmethylated CpG binding