Recombinant Human CYP11A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CYP11A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CYP11A1-4529H
Product Overview : CYP11A1 MS Standard C13 and N15-labeled recombinant protein (NP_001093243) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 42.6 kDa
AA Sequence : MAPEATKNFL PLLDAVSRDF VSVLHRRIKK AGSGNYSGDI SDDLFRFAFE SITNVIFGER QGMLEEVVNP EAQRFIDAIY QMFHTSVPML NLPPDLFRLF RTKTWKDHVA AWDVIFSKAD IYTQNFYWEL RQKGSVHHDY RGILYRLLGD SKMSFEDIKA NVTEMLAGGV DTTSMTLQWH LYEMARNLKV QDMLRAEVLA ARHQAQGDMA TMLQLVPLLK ASIKETLRLH PISVTLQRYL VNDLVLRDYM IPAKTLVQVA IYALGREPTF FFDPENFDPT RWLSKDKNIT YFRNLGFGWG VRQCLGRRIA ELEMTIFLIN MLENFRVEIQ HLSDVGTTFN LILMPEKPIS FTFWPFNQEA TQQTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CYP11A1 cytochrome P450 family 11 subfamily A member 1 [ Homo sapiens (human) ]
Official Symbol : CYP11A1
Synonyms : CYP11A1; cytochrome P450, family 11, subfamily A, polypeptide 1; CYP11A, cytochrome P450, subfamily XIA (cholesterol side chain cleavage); cholesterol side-chain cleavage enzyme, mitochondrial; cholesterol monooxygenase (side chain cleaving); P450SCC; steroid 20-22-lyase; cytochrome P450 11A1; cytochrome P450(scc); cytochrome P450C11A1; cholesterol 20-22 desmolase; cholesterol monooxygenase (side-chain cleaving); cytochrome P450, subfamily XIA (cholesterol side chain cleavage); CYP11A; CYPXIA1;
Gene ID : 1583
mRNA Refseq : NM_001099773
Protein Refseq : NP_001093243
MIM : 118485
UniProt ID : P05108

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