Recombinant Human CYP2C9 protein, MYC/DDK-tagged

• Cat.No.: CYP2C9-531H
• Product Overview: Recombinant Human CYP2C9 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.4 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 [ Homo sapiens ]
• Official Symbol: CYP2C9
• Synonyms: CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9; CYP2C10, cytochrome P450, subfamily IIC (mephenytoin 4 hydroxylase), polypeptide 9; cytochrome P450 2C9; P450IIC9; cytochrome P-450MP; cytochrome P450 PB-1; microsomal monooxygenase; xenobiotic monooxygenase; flavoprotein-linked monooxygenase; cytochrome P-450 S-mephenytoin 4-hydroxylase; CPC9; CYP2C; CYP2C10; CYPIIC9; MGC88320; MGC149605
• Gene ID: 1559
• mRNA Refseq: NM_000771
• Protein Refseq: NP_000762
• MIM: 601130
• UniProt ID: P11712
• Chromosome Location: 10q24.1
• Pathway: Arachidonate Epoxygenase / Epoxide Hydrolase, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem
• Function: (R)-limonene 6-monooxygenase activity; (S)-limonene 6-monooxygenase activity; (S)-limonene 7-monooxygenase activity; caffeine oxidase activity; drug binding; electron carrier activity; heme binding; metal ion binding; monooxygenase activity; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; steroid hydroxylase activity