Recombinant Human CYP2C9/NADPH protein, Active CYP2C9-363H

Recombinant Human CYP2C9/NADPH protein, Active


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Recombinant Human CYP2C9/NADPH protein, Active

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Cat.No. : CYP2C9-363H
Product Overview : This is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP2C9 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation.
Source : Pichia pastoris
Species : Human
Form : Lyophilized powder
Molecular Mass : 55 Kda
Notes : Centrifuge the vial prior to opening
Storage : Stable for 1 year as supplied. Store dry powder at -20 centigrade. Reconstitute in 25 mM Potassium Phosphate buffer, pH 7.7. Not recommended to be stored as solution. If storing as solution, aliquot and store at -80 centigrade. Avoid repeated freeze/thaw cycles and use aliquots within one month (the human CYP2C9 will lose approximately 10% activity per week when stored at -80 centigrade). Thaw aliquots rapidly at 37 centigrade and place on ice until use (thawed aliquots should be used within 4 hours).
Reconstitution : 25 mM Potassium Phosphate buffer, pH 7.7
Gene Name : CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 [ Homo sapiens ]
Official Symbol : CYP2C9
Synonyms : CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9; CYP2C10, cytochrome P450, subfamily IIC (mephenytoin 4 hydroxylase), polypeptide 9; cytochrome P450 2C9; P450IIC9; cytochrome P-450MP; cytochrome P450 PB-1; microsomal monooxygenase; xenobiotic monooxygenase; flavoprotein-linked monooxygenase; cytochrome P-450 S-mephenytoin 4-hydroxylase; CPC9; CYP2C; CYP2C10; CYPIIC9; MGC88320; MGC149605;
Gene ID : 1559
mRNA Refseq : NM_000771
Protein Refseq : NP_000762
MIM : 601130
UniProt ID : P11712
Chromosome Location : 10q24.1
Pathway : Arachidonate Epoxygenase / Epoxide Hydrolase, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem;
Function : (R)-limonene 6-monooxygenase activity; (S)-limonene 6-monooxygenase activity; (S)-limonene 7-monooxygenase activity; caffeine oxidase activity; drug binding; electron carrier activity; heme binding; metal ion binding; monooxygenase activity; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; steroid hydroxylase activity;

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