Recombinant Human CYP2D6/NADPH protein, Active
Cat.No. : | CYP2D6-363H |
Product Overview : | This is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP2D6 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation. |
- Specification
- Gene Information
- Related Products
Source : | Pichia pastoris |
Species : | Human |
Form : | Lyophilized powder |
Molecular Mass : | 55 Kda |
Notes : | Centrifuge the vial prior to opening |
Storage : | Stable for 1 year as supplied. Store dry powder at -20 centigrade. Reconstitute in 100 mM Phosphate buffer, pH 7.7. Not recommended to be stored as solution. If storing as solution, aliquot and store at -80 centigrade. Avoid repeated freeze/thaw cycles and use aliquots within one month (the human CYP2D6 will lose approximately 10% activity per week when stored at -80 centigrade). Thaw aliquots rapidly at 37 centigrade and place on ice until use (thawed aliquots should be used within 4 hours). |
Reconstitution : | 100 mM Potassium Phosphate buffer, pH 7.7 |
Gene Name : | CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 [ Homo sapiens ] |
Official Symbol : | CYP2D6 |
Synonyms : | CYP2D6; cytochrome P450, family 2, subfamily D, polypeptide 6; CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., metabolizing), polypeptide 6; cytochrome P450 2D6; CPD6; CYP2D; P450 DB1; P450C2D; cytochrome P450-DB1; microsomal monooxygenase; xenobiotic monooxygenase; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2; CYP2DL1; CYPIID6; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1; MGC120389; MGC120390; |
Gene ID : | 1565 |
mRNA Refseq : | NM_000106 |
Protein Refseq : | NP_000097 |
MIM : | 124030 |
UniProt ID : | P10635 |
Chromosome Location : | 22q13.1 |
Pathway : | Biological oxidations, organism-specific biosystem; Codeine and morphine metabolism, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem; Metabolism, organism-specific biosystem; |
Function : | aromatase activity; drug binding; electron carrier activity; heme binding; heme binding; metal ion binding; monooxygenase activity; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; |
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CYP2D6-0003H | Recombinant Human CYP2D6 Protein (P34-R497), Tag Free | +Inquiry |
CYP2D6-78H | Active Recombinant Human CYP2D6 Protein | +Inquiry |
CYP2D6-0004H | Recombinant Human CYP2D6 Protein (P34-R497), His tagged | +Inquiry |
CYP2D6-3401H | Recombinant Human CYP2D6 Protein, DDK-tagged | +Inquiry |
◆ Lysates | ||
CYP2D6-7112HCL | Recombinant Human CYP2D6 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2135 | Cytochrome P450 2D6 Inhibitor Screening Kit | +Inquiry |
Kit-2134 | Cytochrome P450 2D6 Fluorometric Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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