Recombinant Human CYP3A4 protein, MYC/DDK-tagged
| Cat.No. : | CYP3A4-18H |
| Product Overview : | Recombinant Human CYP3A4 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
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| Species : | Human |
| Source : | HEK293 |
| Tag : | DDK&Myc |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name | CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 [ Homo sapiens ] |
| Official Symbol | CYP3A4 |
| Synonyms | CYP3A4; cytochrome P450, family 3, subfamily A, polypeptide 4; CYP3A3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450 3A4; nifedipine oxidase; cytochrome P450 3A3; cytochrome P450 HLp; cytochrome P450-PCN1; cytochrome P450 NF-25; albendazole sulfoxidase; quinine 3-monooxygenase; albendazole monooxygenase; P450-III, steroid inducible; glucocorticoid-inducible P450; taurochenodeoxycholate 6-alpha-hydroxylase; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1; MGC126680; |
| Gene ID | 1576 |
| mRNA Refseq | NM_017460 |
| Protein Refseq | NP_059488 |
| MIM | 124010 |
| UniProt ID | P08684 |
| Chromosome Location | 7q21.1 |
| Pathway | Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Biological oxidations, organism-specific biosystem; Codeine and morphine metabolism, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; |
| Function | albendazole monooxygenase activity; caffeine oxidase activity; electron carrier activity; enzyme binding; heme binding; iron ion binding; metal ion binding; monooxygenase activity; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxygen binding; quinine 3-monooxygenase activity; steroid binding; steroid hydroxylase activity; taurochenodeoxycholate 6alpha-hydroxylase activity; testosterone 6-beta-hydroxylase activity; vitamin D 24-hydroxylase activity; vitamin D3 25-hydroxylase activity; |
Not For Human Consumption!
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