Recombinant Human Cystatin E/M, His-tagged

• Cat.No.: CST6-4988H
• Product Overview: Recombinant human CST6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is a secretable protein that influences osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.
• Concentration: 0.5 mg/ml
• Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 0.1M NaCl.
• Purity: > 95 % by SDS - PAGE
• Sequence: 29-149 amino acids: MGSSHHHHHH SSGLVPRGSH MRPQERMVGE LRDLSPDDPQ VQKAAQAAVA SYNMGSNSIY YFRDTHIIKA QSQLVAGIKY FLTMEMGSTD CRKTRVTGDH VDLTTCPLAA GAQQEKLRCD FEVLVVPWQN SSQLLKHNCV QM
• Molecular Mass: 15.9 kDa
• Applications: SDS-PAGE
• Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: CST6 cystatin E/M [ Homo sapiens ]
• Official Symbol: CST6
• Synonyms: CST6; Cystatin E/M; cystatin-M; cystatin 6; cystatin M; cystatin-6; cystatin-E; cysteine proteinase inhibitor
• Gene ID: 1474
• mRNA Refseq: NM_001323
• Protein Refseq: NP_001314
• MIM: 601891
• UniProt ID: Q15828
• Chromosome Location: 11q13
• Function: cysteine-type endopeptidase inhibitor activity; peptidase inhibitor activity