Description : |
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
47 kDa |
AA Sequence : |
MTRKQAVNSSRPGRPPKRSLGVLQE NARLLTHAVPGLLSPGLITPTGITA AAMAEAMKLQKMKLMAMNTLQGNGS QNGTESEPDDLNSNTGGSESSWDKD KMQSPFAAPGPQHGIAHAALAGQPG IGGAPTLNPLQQNHLLTNRLDLPFM MMPHPLLPVSLPPASVAMAMNQMNH LNTIANMAAAAQIHSPLSRAGTSVI KERIPESPSPAPSLEENHRPGSQTS SHTSSSVSSSPSQMDHHLERMEEVP VQIPIMKSPLDKIQLTPGQALPAGF PGPFIFADSLSSVETLLTNIQGLLK VALDNARIQEKQIQQEKKELRLELY REREIRENLERQLAVELQSRTTMQK RLKKEKKTKRKLQEALEFESKRREQ VEQALKQATTSDSGLRMLKDTGIPD IEIENNGTPHDSAAMQGGNYYCLEM AQQLYSATRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |