Recombinant Human DCN Protein, GST-tagged

• Cat.No.: DCN-2398H
• Product Overview: Human DCN full-length ORF ( AAH05322, 1 a.a. - 359 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.23 kDa
• AA Sequence: MKATIILLLLAQVSWAGPFQQRGLF DFMLEDEASGIGPEVPDDRDFEPSL GPVCPFRCQCHLRVVQCSDLGLDKV PKDLPPDTTLLDLQNNKITEIKDGD FKNLKNLHALILVNNKISKVSPGAF TPLVKLERLYLSKNQLKELPEKMPK TLQELRAHENEITKVRKVTFNGLNQ MIVIELGTNPLKSSGIENGAFQGMK KLSYIRIADTNITSIPQGLPPSLTE LHLDGNKISRVDAASLKGLNNLAKL GLSFNSISAVDNGSLANTPHLRELH LDNNKLTRVPGGLAEHKYIQVVYLH NNNISVVGSSDFCPPGHNTKKASYS GVSLFSNPVQYWEIQPSTFRCVYVR SAIQLGNYK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DCN decorin [ Homo sapiens ]
• Official Symbol: DCN
• Synonyms: DCN; decorin; decorin proteoglycan; DSPG2; SLRR1B; PG-S2; bone proteoglycan II; proteoglycan core protein; small leucine-rich protein 1B; dermatan sulphate proteoglycans II; CSCD; PG40; PGII; PGS2
• Gene ID: 1634
• mRNA Refseq: NM_001920
• Protein Refseq: NP_001911
• MIM: 125255
• UniProt ID: P07585