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Recombinant Human DCTN2 Protein, GST-tagged

Cat.No. : DCTN2-2411H
Product Overview : Human DCTN2 full-length ORF ( AAH00718.1, 1 a.a. - 401 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 70.6 kDa
AA Sequence : MADPKYADLPGIARNEPDVYETSDL PEDDQAEFDAEELTSTSVEHIIVNP NAAYDKFKDKRVGTKGLDFSDRIGK TKRTGYESGEYEMLGEGLGVKETPQ QKYQRLLHEVQELTTEVEKIKTTVK ESATEEKLTPVLLAKQLAALKQQLV ASHLEKLLGPDAAINLTDPDGALAK RLLLQLEATKNSKGGSGGKTTGTPP DSSLVTYELHSRPEQDKFSQAAKVA ELEKRLTELETAVRCDQDAQNPLSA GLQGACLMETVELLQAKVSALDLAV LDQVEARLQSVLGKVNEIAKHKASV EDADTQSKVHQLYETIQRWSPIAST LPELVQRLVTIKQLHEQAMQFGQLL THLDTTQQMIANSLKDNTTLLTQVQ TTMRENLATVEGNFASIDERMKKLG K
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DCTN2 dynactin 2 (p50) [ Homo sapiens ]
Official Symbol : DCTN2
Synonyms : DCTN2; dynactin 2 (p50); dynactin subunit 2; DCTN 50; RBP50; p50 dynamitin; dynactin complex 50 kD subunit; dynactin complex 50 kDa subunit; 50 kD dynein-associated polypeptide; 50 kDa dynein-associated polypeptide; DCTN50; DYNAMITIN;
Gene ID : 10540
mRNA Refseq : NM_006400
Protein Refseq : NP_006391
MIM : 607376
UniProt ID : Q13561

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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