Recombinant Human DDX27 Protein, GST-tagged

• Cat.No.: DDX27-2480H
• Product Overview: Human DDX27 full-length ORF ( ADR83262.1, 1 a.a. - 796 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 87.6 kDa
• AA Sequence: MVLAQRRRGGCEKLRAGPQAVLASG SGFCDNMLADLGLIGTIGEDDEVPV EPESDSGDEEEEGPIVLGRRQKALG KNRSADFNPDFVFTEKEGTYDGSWA LADVMSQLKKKRAATTLDEKIEKVR KKRKTEDKEAKSGKLEKEKEAKEGS EPKEQEDLQENDEEGSEDEASETDY SSADENILTKADTLKVKDRKKKKKK GQEAGGFFEDASQYDENLSFQDMNL SRPLLKAITAMGFKQPTPIQKACIP VGLLGKDICACAATGTGKTAAFALP VLERLIYKPRQAPVTRVLVLVPTRE LGIQVHSVTRQLAQFCNITTCLAVG GLDVKSQEAALRAAPDILIATPGRL IDHLHNCPSFHLSSIEVLILDEADR MLDEYFEEQMKEIIRMCSHHRQTML FSATMTDEVKDLASVSLKNPVRIFV NSNTDVAPFLRQEFIRIRPNREGDR EAIVAALLTRTFTDHVMLFTQTKKQ AHRMHILLGLMGLQVGELHGNLSQT QRLEALRRFKDEQIDILVATDVAAR GLDIEGVKTVINFTMPNTIKHYVHR VGRTARAGRAGRSVSLVGEDERKML KEIVKAAKAPVKARILPQDVILKFR DKIEKMEKDVYAVLQLEAEEKEMQQ SEAQINTAKRLLEKGKEAVVQEPER SWFQTKEERKKEKIAKALQEFDLAL RGKKKRKKFMKDAKKKGEMTAEERS QFEILKAQMFAERLAKRNRRAKRAR AMPEEEPVRGPAKKQKQGKKSVFDE ELTNTSKKALKQYRAGPSFEERKQL GLPHQRRGGNFKSKSRYKRRK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [ Homo sapiens ]
• Official Symbol: DDX27
• Synonyms: DDX27; DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 27; probable ATP-dependent RNA helicase DDX27; dJ686N3.1; DRS1; DEAD box protein 27; RNA helicase-like protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 27; RHLP; Rrp3p; PP3241; HSPC259; MGC1018; FLJ12917; FLJ20596; FLJ22238; MGC163147; DKFZp667N057
• Gene ID: 55661
• mRNA Refseq: NM_017895
• Protein Refseq: NP_060365
• MIM: 616621
• UniProt ID: Q96GQ7