Recombinant Human DHCR7 Protein, GST-tagged
Cat.No. : | DHCR7-2582H |
Product Overview : | Human DHCR7 full-length ORF ( NP_001351.1, 1 a.a. - 475 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 80.9 kDa |
AA Sequence : | MAAKLQPNIPKAKSLDGVTNDRTAS QGQWGRAWEVDWFSLASVIFLLLFA PFIVYYFIMACDQYSCALTGPVVDI VTGHARLSDIWAKTPPITRKAAQLY TLWVTFQVLLYTSLPDFCHKFLPGY VGGIQEGAVTPAGVVNKYQINGLQA WLLTHLLWFANAHLLSWFSPTIIFD NWIPLLWCANILGYAVSTFAMVKGY FFPTSARDCKFTGNFFYNYMMGIEF NPRIGKWFDFKLFFNGRPGIVAWTL INLSFAAKQRELHSHVTNAMVLVNV LQAIYVIDFFWNETWYLKTIDICHD HFGWYLGWGDCVWLPYLYTLQGLYL VYHPVQLSTPHAVGVLLLGLVGYYI FRVANHQKDLFRRTDGRCLIWGRKP KVIECSYTSADGQRHHSKLLVSGFW GVARHFNYVGDLMGSLAYCLACGGG HLLPYFYIIYMAILLTHRCLRDEHR CASKYGRDWERYTAAVPYRLLPGIF |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DHCR7 7-dehydrocholesterol reductase [ Homo sapiens ] |
Official Symbol : | DHCR7 |
Synonyms : | DHCR7; 7-dehydrocholesterol reductase; SLOS, Smith Lemli Opitz syndrome; 7-DHC reductase; sterol delta-7-reductase; putative sterol reductase SR-2; delta-7-dehydrocholesterol reductase; SLOS; |
Gene ID : | 1717 |
mRNA Refseq : | NM_001163817 |
Protein Refseq : | NP_001157289 |
MIM : | 602858 |
UniProt ID : | Q9UBM7 |
Products Types
◆ Recombinant Protein | ||
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DHCR7-1516R | Recombinant Rat DHCR7 Protein, His (Fc)-Avi-tagged | +Inquiry |
DHCR7-2800H | Recombinant Human DHCR7 Protein, His-tagged, OVA Conjugated | +Inquiry |
DHCR7-479H | Recombinant Human DHCR7 Protein, His/GST-tagged | +Inquiry |
DHCR7-11477Z | Recombinant Zebrafish DHCR7 | +Inquiry |
◆ Lysates | ||
DHCR7-6949HCL | Recombinant Human DHCR7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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