Recombinant Human DIABLO Protein (A56-D239), Tag Free
Cat.No. : | DIABLO-0877H |
Product Overview : | Recombinant Human GG-Diablo(A56-D239 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | A56-D239 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | DIABLO diablo, IAP-binding mitochondrial protein [ Homo sapiens (human) ] |
Official Symbol : | DIABLO |
Synonyms : | DIABLO; diablo, IAP-binding mitochondrial protein; diablo homolog, mitochondrial; DFNA64; DIABLO S; FLJ10537; FLJ25049; second mitochondria derived activator of caspase; SMAC; 0610041G12Rik; mitochondrial Smac protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; SMAC3; DIABLO-S; |
Gene ID : | 56616 |
mRNA Refseq : | NM_019887 |
Protein Refseq : | NP_063940 |
MIM : | 605219 |
UniProt ID : | Q9NR28 |
Products Types
◆ Recombinant Protein | ||
DIABLO-0878H | Recombinant Human DIABLO Protein (A56-D239), GST tagged | +Inquiry |
DIABLO-2373M | Recombinant Mouse DIABLO Protein, His (Fc)-Avi-tagged | +Inquiry |
DIABLO-001H | Recombinant Human DIABLO Protein, His-GST-tagged | +Inquiry |
DIABLO-2619H | Recombinant Human DIABLO Protein, GST-tagged | +Inquiry |
DIABLO-2618H | Recombinant Human DIABLO Protein | +Inquiry |
◆ Lysates | ||
DIABLO-6927HCL | Recombinant Human DIABLO 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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