Recombinant Human DIMT1 Protein, GST-tagged

• Cat.No.: DIMT1-5154H
• Product Overview: Human DIMT1L full-length ORF ( NP_055288.1, 1 a.a. - 313 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61.6 kDa
• AA Sequence: MPKVKSGAIGRRRGRQEQRRELKSA GGLMFNTGIGQHILKNPLIINSIID KAALRPTDVVLEVGPGTGNMTVKLL EKAKKVVACELDPRLVAELHKRVQG TPVASKLQVLVGDVLKTDLPFFDTC VANLPYQISSPFVFKLLLHRPFFRC AILMFQREFALRLVAKPGDKLYCRL SINTQLLARVDHLMKVGKNNFRPPP KVESSVVRIEPKNPPPPINFQEWDG LVRITFVRKNKTLSAAFKSSAVQQL LEKNYRIHCSVHNIIIPEDFSIADK IQQILTSTGFSDKRARSMDIDDFIR LLHGFNAEGIHFS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DIMT1 DIM1 dimethyladenosine transferase 1 homolog [ Homo sapiens (human) ]
• Official Symbol: DIMT1
• Synonyms: DIMT1L; DIMT1; DIM1 dimethyladenosine transferase 1 homolog; DIM1; DIMT1L; HUSSY5; HSA9761; probable dimethyladenosine transferase; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; 18S rRNA dimethylase; DIM1 dimethyladenosine transferase 1-like; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; dimethyladenosine transferase; probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; probable 18S rRNA dimethylase; probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; EC 2.1.1.183
• Gene ID: 27292
• mRNA Refseq: NM_001348076
• Protein Refseq: NP_001335005
• MIM: 612499
• UniProt ID: Q9UNQ2