Recombinant Human DNAJB4 Protein, GST-tagged

• Cat.No.: DNAJB4-2738H
• Product Overview: Human DNAJB4 full-length ORF ( AAH34721, 1 a.a. - 337 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 62.81 kDa
• AA Sequence: MGKDYYCILGIEKGASDEDIKKAYR KQALKFHPDKNKSPQAEEKFKEVAE AYEVLSDPKKREIYDQFGEEGLKGG AGGTDGQGGTFRYTFHGDPHATFAA FFGGSNPFEIFFGRRMGGGRDSEEM EIDGDPFSAFGFSMNGYPRDRNSVG PSRLKQDPPVIHELRVSLEEIYSGC TKRMKISRKRLNADGRSYRSEDKIL TIEIKKGWKEGTKITFPREGDETPN SIPADIVFIIKDKDHPKFKRDGSNI IYTAKISLREALCGCSINVPTLDGR NIPMSVNDIVKPGMRRRIIGYGLPF PKNPDQRGDLLIEFEVSFPDTISSS SKEVLRKHLPAS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ]
• Official Symbol: DNAJB4
• Synonyms: DNAJB4; DnaJ (Hsp40) homolog, subfamily B, member 4; dnaJ homolog subfamily B member 4; HLJ1; HSP40 homolog; heat shock protein 40 homolog; human liver DnaJ-like protein; DnaJ-like heat shock protein 40; heat shock 40 kDa protein 1 homolog; DjB4; DNAJW
• Gene ID: 11080
• mRNA Refseq: NM_007034
• Protein Refseq: NP_008965
• MIM: 611327
• UniProt ID: Q9UDY4