Recombinant Human DNAJB4 Protein, MYC/DDK-tagged

• Cat.No.: DNAJB4-2390H
• Product Overview: Recombinant Human DNAJB4 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 37.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ]
• Official Symbol: DNAJB4
• Synonyms: DjB4; DNAJW; HLJ1
• Gene ID: 11080
• mRNA Refseq: NM_007034
• Protein Refseq: NP_008965
• MIM: 611327
• UniProt ID: Q9UDY4