Recombinant Human DNAJB4 Protein, MYC/DDK-tagged

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Recombinant Human DNAJB4 Protein, MYC/DDK-tagged

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Cat.No. : DNAJB4-2390H
Product Overview : Recombinant Human DNAJB4 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 37.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ]
Official Symbol : DNAJB4
Synonyms : DjB4; DNAJW; HLJ1
Gene ID : 11080
mRNA Refseq : NM_007034
Protein Refseq : NP_008965
MIM : 611327
UniProt ID : Q9UDY4

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