Recombinant Human DPH2
| Cat.No. : | DPH2-28432TH |
| Product Overview : | Recombinant full length Human DPH2 with a N terminal proprietary tag; Predicted MWt 79.90 kDa. |
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| Species : | Human |
| Source : | Wheat Germ |
| Tag : | Non |
| Protein Length : | 489 amino acids |
| Description : | This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. |
| Molecular Weight : | 79.900kDa inclusive of tags |
| Tissue specificity : | Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes. |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MESMFSSPAEAALQRETGVPGLLTPLPDLDGVYELERVAG FVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFIL GDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPV AFVLRQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHA LEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFG RRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLG WAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARD ARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALG RPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILA PCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPP ESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQL ELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIA IAYEDEGSG |
| Sequence Similarities : | Belongs to the DPH1/DPH2 family. DPH2 subfamily. |
| Gene Name | DPH2 DPH2 homolog (S. cerevisiae) [ Homo sapiens ] |
| Official Symbol | DPH2 |
| Synonyms | DPH2; DPH2 homolog (S. cerevisiae); diptheria toxin resistance protein required for diphthamide biosynthesis like 2 (S. cerevisiae) , DPH2 like 2 (S. cerevisiae) , DPH2L2; diphthamide biosynthesis protein 2; |
| Gene ID | 1802 |
| mRNA Refseq | NM_001039589 |
| Protein Refseq | NP_001034678 |
| MIM | 603456 |
| Uniprot ID | Q9BQC3 |
| Chromosome Location | 1p34 |
Not For Human Consumption!
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