| Species : |
Human |
| Source : |
Wheat Germ |
| Tag : |
Non |
| Protein Length : |
489 amino acids |
| Description : |
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. |
| Molecular Weight : |
79.900kDa inclusive of tags |
| Tissue specificity : |
Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes. |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MESMFSSPAEAALQRETGVPGLLTPLPDLDGVYELERVAG FVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFIL GDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPV AFVLRQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHA LEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFG RRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLG WAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARD ARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALG RPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILA PCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPP ESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQL ELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIA IAYEDEGSG |
| Sequence Similarities : |
Belongs to the DPH1/DPH2 family. DPH2 subfamily. |
