Recombinant Human DPP10 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: DPP10-212H
• Product Overview: DPP10 MS Standard C13 and N15-labeled recombinant protein (NP_065919) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 90.9 kDa
• AA Sequence: MNQTASVSHHIKCQPSKTIKELGSN SPPQRNWKGIAIALLVILVVCSLIT MSVILLTPDELTNSSETRLSLEDLF RKDFVLHDPEARWINDTDVVYKSEN GHVIKLNIETNATTLLLENTTFVTF KASRHSVSPDLKYVLLAYDVKQIFH YSYTASYVIYNIHTREVWELNPPEV EDSVLQYAAWGVQGQQLIYIFENNI YYQPDIKSSSLRLTSSGKEEIIFNG IADWLYEEELLHSHIAHWWSPDGER LAFLMINDSLVPTMVIPRFTGALYP KGKQYPYPKAGQMNPTIKLYVVNLY GPTHTLELMPPDSFKSREYYITMVK WVSNTKTVVRWLNRAQNISILTVCE TTTGACSKKYEMTSDTWLSQQNEEP VFSRDGSKFFMTVPVKQGGRGEFHH IAMFLIQSKSEQITVRHLTSGNWEV IKILAYDETTQKIYFLSTESSPRGR QLYSASTEGLLNRQCISCNFMKEQC TYFDASFSPMNQHFLLFCEGPRVPV VSLHSTDNPAKYFILESNSMLKEAI LKKKIGKPEIKILHIDDYELPLQLS LPKDFMDRNQYALLLIMDEEPGGQL VTDKFHIDWDSVLIDMDNVIVARFD GRGSGFQGLKILQEIHRRLGSVEVK DQITAVKFLLKLPYIDSKRLSIFGK GYGGYIASMILKSDEKLFKCGSVVA PITDLKLYASAFSERYLGMPSKEES TYQAASVLHNVHGLKEENILIIHGT ADTKVHFQHSAELIKHLIKAGVNYT MQVYPDEGHNVSEKSKYHLYSTILK FFSDCLKEEISVLPQEPEEDETRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DPP10 dipeptidyl-peptidase 10 (non-functional) [ Homo sapiens (human) ]
• Official Symbol: DPP10
• Synonyms: DPP10; dipeptidyl-peptidase 10 (non-functional); dipeptidyl peptidase 10, dipeptidylpeptidase 10; inactive dipeptidyl peptidase 10; DPRP3; DPP X; DPRP-3; dipeptidyl peptidase X; dipeptidyl peptidase 10; dipeptidyl peptidase like protein 2; dipeptidyl peptidase-like protein 2; dipeptidyl peptidase IV-related protein 3; DPL2; DPPY
• Gene ID: 57628
• mRNA Refseq: NM_020868
• Protein Refseq: NP_065919
• MIM: 608209
• UniProt ID: Q8N608