Recombinant Human DPPA4 Protein, GST-tagged

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Recombinant Human DPPA4 Protein, GST-tagged

DPPA4 Related Products

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Cat.No. : DPPA4-2854H
Product Overview : Human DPPA4 full-length ORF ( AAH32846.2, 1 a.a. - 304 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 59.9 kDa
AA Sequence : MLRGSASSTS MEKAKGKEWT STEKSREEDQ QASNQPNSIA LPGTSAKRTK EKMSVKGSKV LCPKKKAEHT DNPRPQKKIP IPPLPSKLPP VNLIHRDILR AWCQQLKLSS KGQKLDAYKR LCAFAYPNQK DFPSTAKEAK IRKSLQKKLK VEKGETSLQS SETHPPEVAL PPVGEPPALE NSTALLEGVN TVVVTTSAPE ALLASWARIS ARARTPEAVE SPQEASGVRW CVVHGKSLPA DTDGWVHLQF HAGQAWVPEK QEGRVSALFL LPASNFPPPH LEDNMLCPKC VHRNKVLIKS LQWE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DPPA4 developmental pluripotency associated 4 [ Homo sapiens ]
Official Symbol : DPPA4
Synonyms : DPPA4; developmental pluripotency associated 4; developmental pluripotency-associated protein 4; FLJ10713; 2410091M23Rik;
Gene ID : 55211
mRNA Refseq : NM_018189
Protein Refseq : NP_060659
MIM : 614125
UniProt ID : Q7L190

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