"DPY30" Related Products

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Recombinant Human DPY30 protein, His-tagged

Cat.No.: DPY30-315H
Product Overview: Recombinant full-length human DPY30 was expressed in E.coli cells using an N-terminal His tag.
Description: As a core subunit of the SET1/MLL histone methyl-transferase complexes, DPY30 modulates H3K4 methylation in vitro, and directly regulates chromosomal H3K4 trimethylation (H3K4me3) throughout the mam-malian genome. The methylation event has been shown to affect embryonic stem cells (ESCs) maintenance and differentiation. Depletion of Dpy-30 does not affect ESC self-renewal, but significantly alters the differentiation potential of ESCs, particularly along the neural lineage.
Source: E.coli
Species: Human
Tag : His
Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
Molecular Mass: 20 kDa
Purity: The purity of DPY30 was determined to be >95% by densitometry.
Applications: Enzyme Assay; WB
Stability: 1 year at -70 centigrade
Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1 μg/μL
Gene Name: histone methyltransferase complex regulatory subunit [ Homo sapiens (human) ]
Official Symbol: DPY30
Synonyms: Cps25; Saf19; HDPY-30
Gene ID: 84661
mRNA Refseq: NM_032574
Protein Refseq: NP_115963
MIM: 612032
UniProt ID: Q9C005

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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