Recombinant Human DRD2 Protein, His-tagged

• Cat.No.: DRD2-17H
• Product Overview: Recombinant protein of Human dopamine receptor D2 (DRD2), transcript variant 1, Ile214-Gln373, with N-terminal His tag, expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 214-373 a.a.
• Description: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
• Molecular Mass: 18.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 50mM Tris, 8M Urea, pH8.0.

Gene Information

• Gene Name: DRD2 dopamine receptor D2 [ Homo sapiens (human) ]
• Official Symbol: DRD2
• Synonyms: DRD2; dopamine receptor D2; D2R; D2DR; D(2) dopamine receptor; dopamine D2 receptor; dopamine receptor D2 isoform; seven transmembrane helix receptor
• Gene ID: 1813
• mRNA Refseq: NM_000795
• Protein Refseq: NP_000786
• MIM: 126450
• UniProt ID: P14416