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Recombinant Human DSC2 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : DSC2-4443H
Product Overview : DSC2 MS Standard C13 and N15-labeled recombinant protein (NP_004940) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 93.77 kDa
AA Sequence : MEAARPSGSWNGALCRLLLLTLAIL IFASDACKNVTLHVPSKLDAEKLVG RVNLKECFTAANLIHSSDPDFQILE DGSVYTTNTILLSSEKRSFTILLSN TENQEKKKIFVFLEHQTKVLKKRHT KEKVLRRAKRRWAPIPCSMLENSLG PFPLFLQQVQSDTAQNYTIYYSIRG PGVDQEPRNLFYVERDTGNLYCTRP VDREQYESFEIIAFATTPDGYTPEL PLPLIIKIEDENDNYPIFTEETYTF TIFENCRVGTTVGQVCATDKDEPDT MHTRLKYSIIGQVPPSPTLFSMHPT TGVITTTSSQLDRELIDKYQLKIKV QDMDGQYFGLQTTSTCIINIDDVND HLPTFTRTSYVTSVEENTVDVEILR VTVEDKDLVNTANWRANYTILKGNE NGNFKIVTDAKTNEGVLCVVKPLNY EEKQQMILQIGVVNEAPFSREASPR SAMSTATVTVNVEDQDEGPECNPPI QTVRMKENAEVGTTSNGYKAYDPET RSSSGIRYKKLTDPTGWVTIDENTG SIKVFRSLDREAETIKNGIYNITVL ASDQGGRTCTGTLGIILQDVNDNSP FIPKKTVIICKPTMSSAEIVAVDPD EPIHGPPFDFSLESSTSEVQRMWRL KAINDTAARLSYQNDPPFGSYVVPI TVRDRLGMSSVTSLDVTLCDCITEN DCTHRVDPRIGGGGVQLGKWAILAI LLGIALLFCILFTLVCGASGTSKQP KVIPDDLAQQNLIVSNTEAPGDDKV YSANGFTTQTVGASAQGVCGTVGSG IKNGGQETIEMVKGGHQTSESCRGA GHHHTLDSCRGGHTEVDNCRYTYSE WHSFTQPRLGEESIRGHTLIKNTRT RPLEQKLISEEDLAANDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : DSC2 desmocollin 2 [ Homo sapiens (human) ]
Official Symbol : DSC2
Synonyms : DSC2; desmocollin 2; DSC3; desmocollin-2; CDHF2; cadherin family member 2; desmosomal glycoprotein II; desmosomal glycoprotein III; desmosomal glycoprotein II/III; DG2; ARVD11; DGII/III; DKFZp686I11137;
Gene ID : 1824
mRNA Refseq : NM_004949
Protein Refseq : NP_004940
MIM : 125645
UniProt ID : Q02487

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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