Recombinant Human DTNBP1 Protein, GST-tagged

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Recombinant Human DTNBP1 Protein, GST-tagged

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Cat.No. : DTNBP1-2902H
Product Overview : Human DTNBP1 full-length ORF ( NP_115498.2, 1 a.a. - 351 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 65.9 kDa
AA Sequence : MLETLRERLL SVQQDFTSGL KTLSDKSREA KVKSKPRTVP FLPKYSAGLE LLSRYEDTWA ALHRRAKDCA SAGELVDSEV VMLSAHWEKK KTSLVELQEQ LQQLPALIAD LESMTANLTH LEASFEEVEN NLLHLEDLCG QCELERCKHM QSQQLENYKK NKRKELETFK AELDAEHAQK VLEMEHTQQM KLKERQKFFE EAFQQDMEQY LSTGYLQIAE RREPIGSMSS MEVNVDMLEQ MDLMDISDQE ALDVFLNSGG EENTVLSPAL GPESSTCQNE ITLQVPNPSE LRAKPPSSSS TCTDSATRDI SEGGESPVVQ SDEEEVQVDT ALATSHTDRE ATPDGGEDSD S
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DTNBP1 dystrobrevin binding protein 1 [ Homo sapiens ]
Official Symbol : DTNBP1
Synonyms : DTNBP1; dystrobrevin binding protein 1; dysbindin; DBND; Dysbindin; HPS7; My031; dysbindin-1; hermansky-Pudlak syndrome 7 protein; SDY; FLJ30031; MGC20210; DKFZp564K192;
Gene ID : 84062
mRNA Refseq : NM_032122
Protein Refseq : NP_115498
MIM : 607145
UniProt ID : Q96EV8

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