Recombinant Human DUS2 Protein, MYC/DDK-tagged

• Cat.No.: DUS2-2711H
• Product Overview: Recombinant Human DUS2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DUS2 dihydrouridine synthase 2 [ Homo sapiens ]
• Official Symbol: DUS2
• Synonyms: DUS2L; SMM1; URLC8
• Gene ID: 54920
• mRNA Refseq: NM_017803.4
• Protein Refseq: NP_060273
• MIM: 609707