Recombinant Human DUSP12 Protein, GST-tagged
Cat.No. : | DUSP12-2925H |
Product Overview : | Human DUSP12 full-length ORF ( AAH06286.1, 1 a.a. - 340 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 63.03 kDa |
AA Sequence : | MLEAPGPSDGCELSNPSASRVSCAG QMLEVQPGLYFGGAAAVAEPDHLRE AGITAVLTVDSEEPSFKAGPGVEDL WRLFVPALDKPETDLLSHLDRCVAF IGQARAEGRAVLVHCHAGVSRSVAI ITAFLMKTDQLPFEKAYEKLQILKP EAKMNEGFEWQLKLYQAMGYEVDTS SAIYKQYRLQKVTEKYPELQNLPQE LFAVDPTTVSQGLKDEVLYKCRKCR RSLFRSSSILDHREGSGPIAFAHKR MTPSSMLTTGRQAQCTSYFIEPVQW MESALLGVMDGQLLCPKCSAKLGSF NWYGEQCSCGRWITPAFQIHKNRVD EMKILPVLGSQTGKI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DUSP12 dual specificity phosphatase 12 [ Homo sapiens ] |
Official Symbol : | DUSP12 |
Synonyms : | DUSP12; dual specificity phosphatase 12; dual specificity protein phosphatase 12; DUSP1; serine/threonine specific protein phosphatase; YVH1; YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog; YVH1 protein-tyrosine phosphatase ortholog; dual specificity tyrosine phosphatase YVH1; |
Gene ID : | 11266 |
mRNA Refseq : | NM_007240 |
Protein Refseq : | NP_009171 |
MIM : | 604835 |
UniProt ID : | Q9UNI6 |
Products Types
◆ Recombinant Protein | ||
DUSP12-794H | Recombinant Human DUSP12 Protein, His (Fc)-Avi-tagged | +Inquiry |
DUSP12-01H | Recombinant Human DUSP12 Protein, Myc/DDK-tagged | +Inquiry |
Dusp12-2681M | Recombinant Mouse Dusp12 Protein, Myc/DDK-tagged | +Inquiry |
DUSP12-1632R | Recombinant Rat DUSP12 Protein, His (Fc)-Avi-tagged | +Inquiry |
DUSP12-12205H | Recombinant Human DUSP12, His-tagged | +Inquiry |
◆ Lysates | ||
DUSP12-6782HCL | Recombinant Human DUSP12 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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