Recombinant Human DUSP22, His-tagged

• Cat.No.: DUSP22-191H
• Product Overview: DUSP22,1-184aa, Human, His tag, E.coli

Specification

• Description: DUSP22 belongs to the protein-tyrosine phosphatase family and contains 1 tyrosine-protein phosphatase domain. This protein activates the Jnk signaling pathway and dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK). Recombinant human DUSP22 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 23.3 kDa (207aa)
• Protein length: 1-184aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGNGMNK ILPGLYIGNF KDARDAEQLS KNKVTHILSV HDSARPMLEG VKYLCIPAAD SPSQNLTRHF KESIKFIHEC RLRGESCLVH CLAGVSRSVT LVIAYIMTVT DFGWEDALHT VRAGRSCANP NVGFQRQLQE FEKHEVHQYR QWLKEEYGES PLQDAEEAKN ILAAPGILKF WAFLRRL
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DUSP22 dual specificity phosphatase 22 [ Homo sapiens ]
• Official Symbol: DUSP22
• Synonyms: DUSP22; dual specificity phosphatase 22; dual specificity protein phosphatase 22; JKAP; JSP1; MKPX; VHX; JSP-1; MKP-x; LMW-DSP2; MAP kinase phosphatase x; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; mitogen-activated protein kinase phosphatase x; low molecular weight dual specificity phosphatase 2; homolog of mouse dual specificity phosphatase LMW-DSP2; LMWDSP2; FLJ35864
• Gene ID: 56940
• mRNA Refseq: NM_020185
• Protein Refseq: NP_064570
• UniProt ID: Q9NRW4
• Chromosome Location: 6pter-q22.33
• Pathway: MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem
• Function: hydrolase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity