Recombinant Human DYRK1A, GST-tagged

• Cat.No.: DYRK1A-19H
• Product Overview: Recombinant human full length DYRK1A, fused with GST tag, was expressed in Baculovirus.

Specification

• Cat. No.: DYRK1A-19H
• Description: DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease.
• Source: Baculovirus
• Molecular Mass: 113 kDa
• Applications: Kinase Assay
• Form: Lyophilized
• Storage: Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
• OfficialSymbol: DYRK1A

Gene Information

• Gene Name: DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [ Homo sapiens (human) ]
• Synonyms: DYRK1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; DYRK; DYRK1; MNBH; dual specificity tyrosine-phosphorylation-regulated kinase 1A
• Gene ID: 1859
• mRNA Refseq: NM_001396
• Protein Refseq: NP_001387
• MIM: 600855
• UniProt ID: Q13627
• Chromosome Location: 21q22.13
• Pathway: Cell Cycle, Mitotic, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem; Mitotic G1-G1/S phases, organism-specific biosystem
• Function: ATP binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding