Recombinant Human DYRK2 Protein, GST-tagged

• Cat.No.: DYRK2-2987H
• Product Overview: Human DYRK2 full-length ORF ( AAH05809, 1 a.a. - 528 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.82 kDa
• AA Sequence: MNDHLHVGSHAHGQIQVQQLFEDNS NKRTVLTTQPNGLTTVGKTGLPVVP ERQLDSIHRRQGSSTSLKSMEGMGK VKATPMTPEQAMKQYMQKLTAFEHH EIFSYPEIYFLGLNAKKRQGMTGGP NNGGYDDDQGSYVQVPHDHVAYRYE VLKVIGKGSFGQVVKAYDHKVHQHV ALKMVRNEKRFHRQAAEEIRILEHL RKQDKDNTMNVIHMLENFTFRNHIC MTFELLSMNLYELIKKNKFQGFSLP LVRKFAHSILQCLDALHKNRIIHCD LKPENILLKQQGRSGIKVIDFGSSC YEHQRVYTYIQSRFYRAPEVILGAR YGMPIDMWSLGCILAELLTGYPLLP GEDEGDQLACMIELLGMPSQKLLDA SKRAKNFVSSKGYPRYCTVTTLSDG SVVLNGGRSRRGKLRGPPESREWGN ALKGCDDPLFLDFLKQCLEWDPAVR MTPGQALRHPWLRRRLPKPPTGEKT SVKRITESTGAITSISKLPPPSSSA SKLRTNLAQMTDANGNIQQRTVLPK LVS
• Applications: Kinase Assay
  Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [ Homo sapiens ]
• Official Symbol: DYRK2
• Synonyms: DYRK2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-phosphorylation-regulated kinase 2; FLJ21217; FLJ21365
• Gene ID: 8445
• mRNA Refseq: NM_003583
• Protein Refseq: NP_003574
• MIM: 603496
• UniProt ID: Q92630