Recombinant Human EARS2 Protein, His-tagged

• Cat.No.: EARS2-1395H
• Product Overview: Recombinant Human EARS2 Protein (Gly247-Ser523) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.8 kDa
  Accurate Molecular Mass: 34 kDa
• Protein length: Gly247-Ser523
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: EARS2 glutamyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens (human) ]
• Official Symbol: EARS2
• Synonyms: EARS2; glutamyl-tRNA synthetase 2, mitochondrial (putative); probable glutamate--tRNA ligase, mitochondrial; glutamate tRNA ligase 2; mitochondrial (putative); KIAA1970; MSE1; gluRS; glutamate--tRNA ligase; glutamate tRNA ligase 2, mitochondrial; probable glutamyl-tRNA synthetase, mitochondrial
• Gene ID: 124454
• mRNA Refseq: NM_001083614
• Protein Refseq: NP_001077083
• MIM: 612799
• UniProt ID: Q5JPH6