Recombinant Human EGLN3, His-tagged

• Cat.No.: EGLN3-12327H
• Product Overview: Recombinant Human EGLN3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-239a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: EGLN3 egl nine homolog 3 (C. elegans) [ Homo sapiens ]
• Official Symbol: EGLN3
• Synonyms: EGLN3; egl nine homolog 3 (C. elegans); EGL nine (C.elegans) homolog 3; egl nine homolog 3; HIF prolyl hydroxylase 3; HIFPH3; PHD3; HPH-1; HPH-3; HIF-PH3; HIF-prolyl hydroxylase 3; egl nine-like protein 3 isoform; hypoxia-inducible factor prolyl hydroxylase 3; prolyl hydroxylase domain-containing protein 3; FLJ21620; MGC125998; MGC125999
• Gene ID: 112399
• mRNA Refseq: NM_022073
• Protein Refseq: NP_071356
• MIM: 606426
• UniProt ID: Q9H6Z9
• Chromosome Location: 14q12
• Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Renal cell carcinoma, organism-specific biosystem; Renal cell carcinoma, conserved biosystem
• Function: L-ascorbic acid binding; iron ion binding; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors