Description : |
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
60.6 kDa |
AA Sequence : |
MFSWVSKDARRKKEPELFQTVAEGL RQLYAQKLLPLEEHYRFHEFHSPAL EDADFDNKPMVLLVGQYSTGKTTFI RHLIEQDFPGMRIGPEPTTDSFIAV MHGPTEGVVPGNALVVDPRRPFRKL NAFGNAFLNRFMCAQLPNPVLDSIS IIDTPGILSGEKQRISRGYDFAAVL EWFAERVDRIILLFDAHKLDISDEF SEVIKALKNHEDKIRVVLNKADQIE TQQLMRVYGALMWSLGKIINTPEVV RVYIGSFWSHPLLIPDNRKLFEAEE QDLFKDIQSLPRNAALRKLNDLIKR ARLAKVHAYIISSLKKEMPNVFGKE SKKKELVNNLGEIYQKIEREHQISP GDFPSLRKMQELLQTQDFSKFQALK PKLLDTVDDMLANDIARLMVMVRQE ESLMPSQVVKGGAFDGTMNGPFGHG YGEGAGEGIDDVEWVVGKDKPTYDE IFYTLSPVNGKITGANAKKEMVKSK LPNTVLGKIWKLADVDKDGLLDDEE FALANHLIKVKLEGHELPADLPPHL VPPSKRRHESGPTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |