Recombinant Human EHMT1 Protein, GST-tagged

• Cat.No.: EHMT1-3136H
• Product Overview: Human EHMT1 full-length ORF ( AAH47504.1, 1 a.a. - 808 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 113.1 kDa
• AA Sequence: MAAADAEAVPARGEPQQDCCVKTEL LGEETPMAADEGSAEKQAGEAHMAA DGETNGSCENSDASSHANAAKHTQD SARVNPQDGTNTLTRIAENGVSERD SEAAKQNHVTADDFVQTSVIGSNGY ILNKPALQAQPLRTTSTLASSLPGH AAKTLPGGAGKGRTPSAFPQTPAAP PATLGEGSADTEDRKLPAPGADVKV HRARKTMPKSVVGLHAASKDPREVR EARDHKEPKEEINKNISDFGRQQLL PPFPSLHQSLPQNQCYMATTKSQTA CLPFVLAAAVSRKKKRRMGTYSLVP KKKTKVLKQRTVIEMFKSITHSTVG SKGEKDLGASSLHVNGESLEMDSDE DDSEELEEDDGHGAEQAAAFPTEDS RTSKESMSEADRAQKMDGESEEEQE SVDTGEEEEGGDESDLSSESSIKKK FLKRKGKTDSPWIKPARKRRRRSRK KPSGALGSESYKSSAGSAEQTAPGD STGYMEVSLDSLDLRVKGILSSQAE GLANGPDVLETDGLQEVPLCSCRME TPKSREITTLANNQCMATESVDHEL GRCTDSVVKYELMRPSNKAPLLVLC EDHRGRMVKHQCCPGCGYFCTAGNF MECQPESSISHRFHKDCASRVNNAS YCPHCGEESSKAKEVTIAKADTTST VTPVPGQEKGSALEGRADTTTGSAA GPPLSEDDKLQGAASHVPEGFDPTG PAGLGRPTPGLSQGPGKETLESALI ALDSEKPKKLRFHPKQLYFSARQGE LQKVLLMLVDGIDPNFKMEHQNKRS PLHAAAEAGHVDICHMLVQFCRLGS PRSRGCLW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EHMT1 euchromatic histone-lysine N-methyltransferase 1 [ Homo sapiens ]
• Official Symbol: EHMT1
• Synonyms: EHMT1; euchromatic histone-lysine N-methyltransferase 1; euchromatic histone methyltransferase 1; histone-lysine N-methyltransferase EHMT1; bA188C12.1; Eu HMTase1; FLJ12879; KIAA1876; KMT1D; H3-K9-HMTase 5; G9a like protein; G9a-like protein 1; lysine N-methyltransferase 1D; histone H3-K9 methyltransferase 5; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; GLP; GLP1; FP13812; EUHMTASE1; Eu-HMTase1; RP11-188C12.1; DKFZp667M072
• Gene ID: 79813
• mRNA Refseq: NM_001145527
• Protein Refseq: NP_001138999
• MIM: 607001
• UniProt ID: Q9H9B1