Active Recombinant Human EHMT1 protein, GST-tagged
Cat.No. : | EHMT1-181H |
Product Overview : | Recombinant Human EHMT1(895-end) fused with GST tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) is in charge of the mono- and demethylation of lysine-9 of histone H3. EHMT1 is found in a multimeric protein complex containing chromatin modifiers, which contributes to silencing of MYC- and E2F-responsive genes during G0 phase of cell cycle. EHMT1 plays a role in epithelial-to-mesenchymal transition and tumor invasion by repressing expression of tumour suppressor genes. Additionally, EHMT1 also methylates non-histone proteins such as lysine-373 of p53. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 380 nmol/min/mg |
Molecular Mass : | 74 kDa |
Purity : | >95% |
Applications : | Methyltransferase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Publication : |
The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation (2019)
|
Gene Name : | EHMT1 euchromatic histone-lysine N-methyltransferase 1 [ Homo sapiens ] |
Official Symbol : | EHMT1 |
Synonyms : | EHMT1; euchromatic histone-lysine N-methyltransferase 1; euchromatic histone methyltransferase 1; histone-lysine N-methyltransferase EHMT1; bA188C12.1; Eu HMTase1; FLJ12879; KIAA1876; KMT1D; H3-K9-HMTase 5; G9a like protein; G9a-like protein 1; lysine N-m |
Gene ID : | 79813 |
mRNA Refseq : | NM_024757 |
Protein Refseq : | NP_079033 |
MIM : | 607001 |
UniProt ID : | Q9H9B1 |
Chromosome Location : | 9 |
Pathway : | Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; |
Function : | histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltransferase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
EHMT1-3136H | Recombinant Human EHMT1 Protein, GST-tagged | +Inquiry |
EHMT1-128H | Recombinant Human EHMT1 Protein, GST-tagged | +Inquiry |
EHMT1-006H | Recombinant Human EHMT1 Protein, GST-tagged | +Inquiry |
EHMT1-2689M | Recombinant Mouse EHMT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EHMT1-27743TH | Recombinant Human EHMT1, His-tagged | +Inquiry |
◆ Lysates | ||
EHMT1-6685HCL | Recombinant Human EHMT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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