Recombinant Human EHMT2 Protein, GST-tagged EHMT2-014H

Recombinant Human EHMT2 Protein, GST-tagged

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Recombinant Human EHMT2 Protein, GST-tagged

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Cat.No. : EHMT2-014H
Product Overview : Recombinant Human EHMT2 protein with a N-terminal GST-tag was expressed in E. coli
Description : This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 75.4 kDa
Purity : ≥70% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to transfer one methyl group to Histone H3 per minute as determined using 200 µM Histone H3 (amino acids 1-21) peptide at 37 centigrade using Methyltransferase Colorimetric Assay Kit.
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
Activity of EHMT2 :

SDS-PAGE analysis of EHMT2 :

Lane 1: MW Markers
Lane 2: G9a (5 µg)
Lane 3: G9a (2.5 µg)

Gene Name : EHMT2 euchromatic histone lysine methyltransferase 2 [ Homo sapiens (human) ]
Official Symbol : EHMT2
Synonyms : EHMT2; euchromatic histone lysine methyltransferase 2; G9A; BAT8; GAT8; NG36; KMT1C; C6orf30; histone-lysine N methyltransferase EHMT2; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; euchromatic histone-lysine N-methyltransferase 2; histone H3-K9 methyltransferase 3; histone-lysine N methyltransferase, H3 lysine-9 specific 3; lysine N-methyltransferase 1C; EC 2.1.1.43
Gene ID : 10919
mRNA Refseq : NM_001289413
Protein Refseq : NP_001276342
MIM : 604599
UniProt ID : Q96KQ7

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