Recombinant Human EHMT2 Protein, GST-tagged

• Cat.No.: EHMT2-014H
• Product Overview: Recombinant Human EHMT2 protein with a N-terminal GST-tag was expressed in E. coli

Specification

• Description: This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: GST
• Molecular Mass: 75.4 kDa
• Purity: ≥70% estimated by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme required to transfer one methyl group to Histone H3 per minute as determined using 200 µM Histone H3 (amino acids 1-21) peptide at 37 centigrade using Methyltransferase Colorimetric Assay Kit.
• Stability: ≥ 6 months
• Storage: -80 centigrade
• Shipping: Dry ice in continental US, may vary elsewhere.

Gene Information

• Gene Name: EHMT2 euchromatic histone lysine methyltransferase 2 [ Homo sapiens (human) ]
• Official Symbol: EHMT2
• Synonyms: EHMT2; euchromatic histone lysine methyltransferase 2; G9A; BAT8; GAT8; NG36; KMT1C; C6orf30; histone-lysine N methyltransferase EHMT2; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; euchromatic histone-lysine N-methyltransferase 2; histone H3-K9 methyltransferase 3; histone-lysine N methyltransferase, H3 lysine-9 specific 3; lysine N-methyltransferase 1C; EC 2.1.1.43
• Gene ID: 10919
• mRNA Refseq: NM_001289413
• Protein Refseq: NP_001276342
• MIM: 604599
• UniProt ID: Q96KQ7