| Description : |
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
128.8 kDa |
| AA Sequence : |
MAAAAGAAAAAAAEGEAPAEMGALL LEKETRGATERVHGSLGDTPRSEET LPKANPDSLEPAGPSSPASVTVTVG DEGADTPVGATPLIGDESENLEGDG DLRGGRILLGHATKSFPSSPSKGGS CPSRAKMSMTGAGKSPPSVQSLAMR LLSMPGAQGAAAAGSEPPPATTSPE GQPKVHRARKTMSKPGNGQPPVPEK RPPEIQHFRMSDDVHSLGKVTSDLA KRRKLNSGGGLSEELGSARRSGEVT LTKGDPGSLEEWETVVGDDFSLYYD SYSVDERVDSDSKSEVEALTEQLSE EEEEEEEEEEEEEEEEEEEEEEEDE ESGNQSDRSGSSGRRKAKKKWRKDS PWVKPSRKRRKREPPRAKEPRGVSN DTSSLETERGFEELPLCSCRMEAPK IDRISERAGHKCMATESVDGELSGC NAAILKRETMRPSSRVALMVLCETH RARMVKHHCCPGCGYFCTAGTFLEC HPDFRVAHRFHKACVSQLNGMVFCP HCGEDASEAQEVTIPRGDGVTPPAG TAAPAPPPLSQDVPGRADTSQPSAR MRGHGEPRRPPCDPLADTIDSSGPS LTLPNGGCLSAVGLPLGPGREALEK ALVIQESERRKKLRFHPRQLYLSVK QGELQKVILMLLDNLDPNFQSDQQS KRTPLHAAAQKGSVEICHVLLQAGA NINAVDKQQRTPLMEAVVNNHLEVA RYMVQRGGCVYSKEEDGSTCLHHAA KIGNLEMVSLLLSTGQVDVNAQDSG GWTPIIWAAEHKHIEVIRMLLTRGA DVTLTDNEENICLHWASFTGSAAIA EVLLNARCDLHAVNYHGDTPLHIAA RESYHDCVLLFLSRGANPELRNKEG DTAWDLTPERSDVWFALQLNRKLRL GVGNRAIRTEKIICRDVARGYENVP IPCVNGVDGEPCPEDYKYISENCET STMNIDRNITHLQHCTCVDDCSSSN CLCGQLSIRCWYDKDGRLLQEFNKI EPPLIFECNQACSCWRNCKNRVVQS GIKVRLQLYRTAKMGWGVRALQTIP QGTFICEYVGELISDAEADVREDDS YLFDLDNKDGEVYCIDARYYGNISR FINHLCDPNIIPVRVFMLHQDLRFP RIAFFSSRDIRTGEELGFDYGDRFW DIKSKYFTCQCGSEKCKHSAEAIAL EQSRLARLDPHPELLPELGSLPPVN TTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
